Hepatitis C is caused by the hepatitis C virus (HCV), which infects and damages the liver. It is mostly transmitted by blood and, in some cases, through sexual intercourse. In the United States, sharing drug needles with someone who has hepatitis C is the most common mode of transmission.
In people with chronic hepatitis C, the virus stays in the liver permanently and can cause fatigue, weight loss, or no symptoms at all. Over time, chronic hepatitis C can cause scarring of the liver (cirrhosis) or liver failure, which can require a liver transplant or result in liver cancer and even death. Approximately 6% of patients with hepatitis C die from complications of the disease.